John M. Mansfield
Professor of Bacteriology
4470 Microbial Sciences Building
1550 Linden Drive
(608) 262-2596
mansfield@bact.wisc.edu
Select Publications
- Mansfield JM, Paulnock DM. Genetic manipulation of African trypanosomes as a tool to dissect the immunobiology of infection. Parasite Immunol. 2008 30:245-53.
- Hansen JK, Demick KP, Mansfield JM, Forest KT. Conserved regions from Neisseria gonorrhoeae pilin are immunosilent and not immunosuppressive. Infect Immun. 2007 75:4138-47.
- Leppert BJ, Mansfield JM, Paulnock DM. The soluble variant surface glycoprotein of African trypanosomes is recognized by a macrophage scavenger receptor and induces I kappa B alpha degradation independently of TRAF6-mediated TLR signaling. J Immunol. 2007 179:548-56.
- Harris TH, Mansfield JM, Paulnock DM. CpG oligodeoxynucleotide treatment enhances innate resistance and acquired immunity to African trypanosomes. Infect Immun. 2007 75:2366-73.
- Harris TH, Cooney NM, Mansfield JM, Paulnock DM. Signal transduction, gene transcription, and cytokine production triggered in macrophages by exposure to trypanosome DNA. Infect Immun. 2006 74:4530-7.
- Curran CS, Demick KP, Mansfield JM. Lactoferrin activates macrophages via TLR4-dependent and -independent signaling pathways. Cell Immunol. 2006 242:23-30.
- Mansfield JM, Paulnock DM. Regulation of innate and acquired immunity in African trypanosomiasis. Parasite Immunol. 2005 27:361-71.
- Dubois ME, Demick KP, Mansfield JM. Trypanosomes expressing a mosaic variant surface glycoprotein coat escape early detection by the immune system. Infect Immun. 2005 73:2690-7.