William H. McClain
Halvorson Professor of Bacteriology, Emeritus
4554 Microbial Sciences Building
1550 Linden Drive
(608)262-3054
wmcclain@wisc.edu
Select Publications
- McClain, W.H. Surprising contribution to aminoacylation and translation of non-Watson-Crick pairs in tRNA. Proc. Natl. Acad. Sci. USA 2006 103: 4570-4575.
- McClain WH, Gabriel K, Lee D, Otten S. Structure-function analysis of tRNA(Gln) in an Escherichia coli knockout strain. RNA. 2004 10:795-804.
- Lee D, McClain WH. Aptamer redesigned tRNA is nonfunctional and degraded in cells. RNA. 2004 10:7-11.
- Choi, H., Gabriel, K., Schneider, J., Otten, S. and McClain, W. H. Recognition of acceptor-stem structure of tRNAAsp by Escherichia coli aspartyl-tRNA synthetase. RNA 2003 9: 386-393.
- Choi, H., Otten, S., Schneider, J. and McClain, W.H. Genetic perturbations of RNA reveal structure-based recognition in protein-RNA interaction. J. Mol. Biol. 2002 324: 573-576.
- Choi H, Otten S, McClain WH. Isolation of novel tRNA(Ala) mutants by library selection in a tRNA(Ala) knockout strain. Biochimie. 2002 84:705-11.
- Moulinier, L., Eiler, S., Eriani, G., Grangloff, J., Thierry, J.-C., Gabriel, K., McClain, W.H. and Moras, D. The structure of an AspRS-tRNAAsp complex reveals a tRNA dependent control mechanism. EMBO J. 2001 20: 5290-5301.
- Chang, K.-Y., Varani, G., Bhattacharya, S., Choi, H. and McClain, W.H. Correlation of deformability at a tRNA recognition site and aminoacylation specificity. Proc. Natl. Acad. Sci. USA 1999 96: 11764-11769.